Influence factors for the differential signal path of intestine stem cells and the repairment of intestinal mucosal
10.3760/cma.j.issn.1673-4912.2015.01.013
- VernacularTitle:小肠干细胞分化的信号通路与肠黏膜修复影响因素研究
- Author:
Ying SUN
- Publication Type:Journal Article
- Keywords:
Stem cells;
Intetinal mucosa;
Inflammation and damage repairment
- From:
Chinese Pediatric Emergency Medicine
2015;22(1):48-51
- CountryChina
- Language:Chinese
-
Abstract:
Intestine is one of the fastest cellular renewal tissues and organs in the body cells,and intestinal mucosal epithelial cells keep self-renewal constantly all the life.Its effect relys on stem cells continued proliferation,differentiation and replaces the outer terminal differentiated cells.Under the stimulation after injury,the repairment of stem cells is initiated,the proliferation and differentiation of intestinal stem cells are stimulated throughout molecular mechanisms.Studys found that intestinal stem cells involve in the repairment of the gut during stress,trauma,anoxia,radioactive damage,inflammatory bowel disease and short bowel syndrome.In this paper,we briefly overviewed the definition,location,and differentiated regulation stem cells,and influence factors in the intestinal repairment.
