Utilization of antibacterials and the rate of drug resistance analysis in a hospital during 2011-2013
10.3760/cma.j.issn.1008-6706.2015.03.015
- VernacularTitle:安徽省蚌埠市第三人民医院2011-2013年抗菌药物消耗量与常见革兰阴性细菌耐药性分析
- Author:
Shiyong ZHANG
;
Guanjun ZHANG
;
Jun CHENG
;
Gangbin WANG
- Publication Type:Journal Article
- Keywords:
Drug resistance,bacterial;
Gram-negative bacteria
- From:
Chinese Journal of Primary Medicine and Pharmacy
2015;22(3):363-366
- CountryChina
- Language:Chinese
-
Abstract:
Objective To analyze utilization of antibiotic drugs and resistance rate of gram negative bacteria in the 3rd People's Hospital of Bengbu during 2011-2013,to provide references for clinical rational use of antimicrobial drugs and reduce bacterial resistance.Methods Retrospective investigation method was used to statistically analyze the pathogenic bacteria culture results,antimicrobial cumulative frequency of each categories and results of drug resistance test.Results The total DDDs of antibacterial drugs reduced year by year,down from 255 456 DDD in 2011 to 155 024 DDD in 2013,cephalosporin and enzyme inhibitors and macrolide consumption ranked increased year by year,the three or four generation cephalosporins and quinolones such amount was reduced year by year,antifungal fungi and carbapenem ranking had no obvious change,cefoperazone shubatan,cefuroxime and etimicin ranking and the dosage ratio did not change significantly,the cefathiamidine,cefepime and aztreonam ranking and the dosage ratio was reduced.Bauman acinetobacter and Pseudomonas aeruginosa to piperacillin-tazobactam resistant rate increased year by year,Bauman acinetobacter to beta lactam antibiotics drugs showed a gradual trend of drug resistance.Conclusion The frequency of antimicrobial drug use showed a declining trend in our hospital,and drug-resistant bacteria rate increased,in order to reduce the resistance present form,we need to more rational use antimicrobial agents.
