Research progress on prevention and treatment of portal vein thrombosis after splenectomy for patients with hepatic cirrhosis
10.3760/cma.j.issn.1007-8118.2015.01.019
- VernacularTitle:肝硬化患者脾切除术后门静脉血栓的防治研究进展
- Author:
Shaocheng LYU
;
Wanqing GU
- Publication Type:Journal Article
- Keywords:
Splenectomy;
Portal vein thrombosis;
Treatment;
Prevention
- From:
Chinese Journal of Hepatobiliary Surgery
2015;21(1):59-63
- CountryChina
- Language:Chinese
-
Abstract:
Portal vein thrombosis is a common though serious complication after splenectomy in patients with liver cirrhosis and portal hypertension.Its pathogenesis may be primarily associated with the coagulation mechanism and the changes of hemorheology.The clinical presentations of portal vein thrombosis after splenectomy depend on the course of disease,as well as site and degree of obstruction.The principle of treatment is to improve microcirculation,relieve the platelet aggregation and prevent further progress of the thrombosis.But in clinical settings,signs and symptoms of portal vein thrombosis were generally atypical.Any misdiagnosis or delayed treatment may expose the patients under risk.This article focuses on the risk factors,potential mechanisms and recent progress on the prevention of post-splenectomy portal vein thrombosis.
