Detection and preanalytical quality control of circulating microRNA
10.3760/cma.j.issn.1009-9158.2015.04.018
- VernacularTitle:循环microRNA检测技术及分析前质量控制
- Author:
Shunwang CAO
;
Xiaomao YIN
;
Lei ZHENG
;
Qian WANG
- Publication Type:Journal Article
- Keywords:
microRNAs;
Clinical laboratory techniques;
Biological markers
- From:
Chinese Journal of Laboratory Medicine
2015;38(4):285-288
- CountryChina
- Language:Chinese
-
Abstract:
Circulating microRNAs (miRNAs) have been confirmed to play an important role in biological processes,such as cell proliferation,differentiation and apoptosis.Founded on the high stability and minimal invasiveness,circulating miRNAs could be applied to the clinical practice as biomarkers.There are many technological approaches and platforms for circulating miRNAs detection but without a consistent protocol.Meanwhile,there are various factors affecting circulating miRNAs detection.In this review,technical factors and preanalytical factors in the circulating miRNA profiling are explored.
