Optimization of Water Decocting Extraction Procedures for Ganyankang Capsules with Orthogonal Design
- VernacularTitle:正交试验法优选肝炎康胶囊的水煎提取制备工艺
- Author:
Junmin LI
;
Juandi WANG
;
Long QIN
;
Ping LI
;
Yumin LI
;
Lingyi ZHANG
- Publication Type:Journal Article
- Keywords:
Ganyankangcapsules;
Orthogonaldesigntest;
Waterdecoctingextraction;
Emodin
- From:
China Pharmacist
2014;(10):1662-1665
- CountryChina
- Language:Chinese
-
Abstract:
Objective: To optimize the water decocting extraction procedures for Ganyangkang capsules by orthogonal design. Methods:Using the extraction yield and emodin content as the indices, the optimal extraction conditions for Ganyankang capsules were studied by L9(34) orthogonal test. Results:The influencing order of the factors was B>A>C (A:extracting time, B:extracting du-ration, C:added water volume) . The optimal preparation conditions were A3 B3 C2 , i. e. adding 10-fold water, decocting extracting 3 times with 2 hours each time. Conclusion:The optimum water decocting extraction procedures is rational and feasible. It can be used in the real preparation.
