Laboratory diagnosis of EBV infection in children
10.3760/cma.j.issn.1009-9158.2015.04.003
- VernacularTitle:儿童EB病毒感染的实验室诊断
- Author:
Zhan MA
;
Hong ZHANG
- Publication Type:Journal Article
- Keywords:
Epstein-barr virus infections;
Viral load;
Clinical laboratory techniques
- From:
Chinese Journal of Laboratory Medicine
2015;38(4):223-225
- CountryChina
- Language:Chinese
-
Abstract:
Epstein-Barr virus (EBV) remains one of the most important pathogens in children,which usually causes acute EBV infection,chronic active EBV infection,hemophagocytic lymphohistiocytosis,lymphoma and other cancers.Therefore,effective laboratory diagnosis is of importance in diagnosis,surveillance,and control of EBV-associated disease.Currently,a variety of detection methods have been applied in clinical laboratories and typical diagnostic assays are always focusing on EBV-DNA and serological tests.Different assays vary in different purposes and applications,which seems to be difficult to choose an appropriate technique.This article aims at systematically analyzing clinical significance of these assays and evaluating the immune functions of EBV infection and the detection of susceptibility genes of EBV-related disease.
