Research progress in relationship between angiogenin-Tie2 signaling pathways and sepsis
10.3760/cma.j.issn.1673-4408.2015.03.022
- VernacularTitle:血管生成素-Tie2信号通路与脓毒症关系的研究进展
- Author:
Yanying CHEN
- Publication Type:Journal Article
- Keywords:
Sepsis;
Ang1;
Ang2;
Tie2;
Inflammation
- From:
International Journal of Pediatrics
2015;42(3):316-319
- CountryChina
- Language:Chinese
-
Abstract:
Angiopoietin(Ang)is a secreted endothelial cell specific growth factor.Ang 2 levels in the body increase in bloodstream during infection.Studies have demonstrated that Ang 2 is a potential therapeutic target in sepsis.This paper reviews the biological function of Ang 2-Tie2 and Ang 2 inhibitors for a potential role of sepsis treatment.
