Preparation Process of Compound Asiaticoside Gel Plasters
- VernacularTitle:复方积雪草苷凝胶贴膏的制备工艺研究
- Author:
Yang LI
;
Chen CHEN
;
Yinke LI
;
Xiao HU
;
Xiangru LIAO
;
Liang HAN
;
Ying CHEN
- Publication Type:Journal Article
- Keywords:
Compoundasiaticoside;
Gelplasters;
Matrix;
Preparation
- From:
China Pharmacist
2014;(10):1672-1674
- CountryChina
- Language:Chinese
-
Abstract:
Objective: To optimize the formula of compound asiaticoside gel plasters, and determine the optimal preparation process. Methods:Using the initial adhesion, viscosity and appearance as the indices, the gel plasters were evaluated by orthogonal design in order to study the effects of various base ratios on the preparation and screen the optimal formula and preparation process. Re-sults:The optimal formula was dihydroxyaluminium aminoacetate∶EDTA∶glycerol∶CMC-Na of 0. 25∶0. 05∶45∶1. Conclusion: Com-pound asiaticoside gel plasters with the optimal formula and preparation technique show good adhesion and uniformity, which can meet the need of large-scale production.
