Clinical Effects of Sodium Hyaluronate Combined with Arthroscopic Debridement on Knee Osteoarthritis
- VernacularTitle:玻璃酸钠联合关节镜清理治疗膝关节炎疗效观察
- Author:
Ming YAO
;
Yiyang YING
;
Manyang WANG
- Publication Type:Journal Article
- Keywords:
Kneeosteoarthritis;
Arthroscopicdebridement;
Sodiumhyaluronate
- From:
China Pharmacist
2014;(10):1716-1718
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To investigate the clinical effects of arthroscopic debridement combined with intra-articular injection of sodi-um hyaluronate in the treatment of knee osteoarthritis. Methods:One hundred and seventy-two cases with knee osteoarthritis were ran-domly divided into the treatment group and the control group. The control group received arthroscopic debridement, while the treatment group received intra-articular injection of 2. 5ml sodium hyaluronate after arthroscopic debridement. Lequence score, Lysholm score and visual analogue scale for pain were compared between the two groups before the treatment and after the 1-week and 3-month treatment, and the clinical effects were compared after the 3-month treatment as well. Results: Lequence score, Lysholm score and visual ana-logue pain scores after the treatment were lower than those before the treatment with significant differences (P <0.01) in the two groups. After the treatment,Lequence score, Lysholm score and visual analogue pain scores of the treatment group was lower than those of the control group with significant differences (P<0. 05 or 0. 01). After the 3-month treatment,the clinical efficacy of the treatment group was better than that of the control group (P<0. 05). Conclusion:Arthroscopic debridement combined with intra-articular injec-tion of sodium hyaluronate in the treatment of knee osteoarthritis has better efficacy than arthroscopic debridement alone. The combina-tion can effectively improve symptoms, which is worthy of clinical promotion.
