Content Change of Icariin in Rujiling Granules after Ray Irradiation
- VernacularTitle:乳疾灵颗粒辐照前后淫羊藿苷含量变化研究
- Author:
Zhenwei ZHANG
;
Nana ZHANG
;
Jixi QIU
;
Xinmin ZHANG
;
Lei SHI
- Publication Type:Journal Article
- Keywords:
Rujilinggranules;
Irradiation;
Icariin;
Contentchange
- From:
China Pharmacist
2014;(10):1768-1769
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To compare the content of icariin in Rujiling granules before and after the ray irradiation. Methods: The column was Thermo ODS-2 HYPERSIL (250 mm × 4. 6 mm,5 μm) with the temperature of 30℃, and the mobile phase was acetoni-trile-0. 033 mol·L-1 potassium dihydrogen phosphate(30∶70) with the flow rate of 1. 0 ml·min-1. The detection wavelength was 265nm. Results:There was a good linear relationship within the range of 3. 44-34. 40μg·ml-1 for icariin (r=0. 999 7, n=6). The average recovery was 98. 18% with RSD of 0. 32%(n=9). Conclusion:The content change of icariin in Rujiling granules before and after the ray irradiation is not statistically significant, which illustrates that the conventional dose irradiation has little effect on icariin.
