Progresses of the pathogenesis of rotavirus infection
10.3760/cma.j.issn.1673-4408.2015.03.018
- VernacularTitle:轮状病毒感染机制新进展
- Author:
Lingling ZHENG
- Publication Type:Journal Article
- Keywords:
Rotavirus;
Innate immunity;
Structural protein;
Nonstructural protein
- From:
International Journal of Pediatrics
2015;42(3):300-304
- CountryChina
- Language:Chinese
-
Abstract:
Rotavirus is the most important pathogen causing severe diarrhea in infants and young children worldwide,and for rotavirus diarrhea there is no specific treatment so far.At present,there are a variety of claims on the pathogenesis of rotavirus infection,but none is conclusive.In the process of infection,rotavirus pathogens must overcome antiviral innate immune response that can replicate in host cell.Rotavirus encoded proteins play an important role in the process of rotavirus infection.This paperreviews the role of rotavirus encoding proteins in the pathogenesis of rotavirus infection.