The application perspective of nuclear magnetic resonance spectroscopy in laboratory medicine
10.3760/cma.j.issn.1009-9158.2015.02.006
- VernacularTitle:核磁共振波谱技术在检验医学中的应用前景
- Author:
Yuzhang JIANG
;
Zhijun LIU
- Publication Type:Journal Article
- Keywords:
Nuclear magnetic resonance spectroscopy;
Laboratory medicine;
Metabolomics;
Serum
- From:
Chinese Journal of Laboratory Medicine
2015;38(2):88-90
- CountryChina
- Language:Chinese
-
Abstract:
Molecular biomarkers could change associated with disease processes.So,the detection of metabolic markers becomes the key to early diagnosis,treatment and prognosis evaluation disease.But the detection of abundant metabolites in body becomes a crux of laboratory medicine at the same time.The recent advances in nuclear magnetic resonance (NMR) spectroscopy reveal the unequivocal value of NMR in metabolomics platforms.NMR spectroscopy has inherently distinct capabilities to identify and quantitatively measure a large amount of low concentration metabolites in a non-destructive manner.The implementation of NMR technology into a multidisciplinary approach to biomarker identification will improve the auxiliary diagnostic ability of laboratory medicine for the disease.
