Molecular cytogenetic pathogenesis of multiple myeloma: reports in the 55th ASH annual meeting
10.3760/cma.j.issn.1009-9921.2014.02.002
- VernacularTitle:多发性骨髓瘤分子细胞遗传学异常及发病机制:第55届美国血液学会年会报道
- Author:
Xiaoqi QIN
;
Gang AN
;
Lugui QIU
- Publication Type:Journal Article
- Keywords:
Multiple myeloma;
Molecular cytogenetics;
ASH annual meeting
- From:
Journal of Leukemia & Lymphoma
2014;23(2):66-69
- CountryChina
- Language:Chinese
-
Abstract:
The effect of molecular cytogenetics in pathogenesis of multiple myeloma (MM) is fundamental.The risk stratification system that based on molecular cytogenetics of MM is widely applicable in the prognosis of MM.The aberration of molecular cytogenetics is the most important marker of MM.At the same time,high-risk MM is associated with intra-clonal tumor heterogeneity and clonal evolution.The research of intra-clonal tumor heterogeneity and clonal evolution which based on the aberration of molecular cytogenetics will provide some additional information of the biology of MM and contribute to the optimum treatment for MM patients.
