Analysis of influencing factors for giving up chemotherapy during initial treatment in elderly multiple myeloma

VernacularTitle:老年多发性骨髓瘤初治患者放弃化疗状况及相关因素分析
Author: Xiangmei HAN ; Qiaomei CHENG ; Jingxiao DANG ; Bin CUI ; Fan ZHANG ; Ling XU
Publication Type:Journal Article
Keywords: Multiple myeloma; Medication compliance
From: Chinese Journal of Geriatrics 2015;34(4):408-410
CountryChina
Language:Chinese
Abstract: Objective To study influencing factors for giving up chemotherapy during initial treatment in elderly patients with multiple myeloma.Methods A total of 156 elderly patients diagnosed as multiple myeloma from 2000-2010 were retrospectively analyzed.And 123 young patients with multiple myeloma were selected as control group.The causes for giving up the chemotherapy and its related factors were recorded and analyzed.Results The rate of giving up the initial chemotherapy was higher in the elderly than in young patients [58.3％ (91/156) vs.35.0％ (43/123),P＜0.05].51.7％ of the elderly patients did not accept chemotherapy after diagnosis.The main factors for giving up the initial chemotherapy in elderly patients were critically ill,economic difficult and the low tolerance.However,the economic difficulty was the first cause in the young group.Conclusions The rate of giving up the chemotherapy in the elderly patients is high.Old age,severe conditions,economic difficulty,and low tolerance are the independent factors.