Effect of preoperative prophylactic parenteral nutrition on prognosis of advanced gastric cancer
10.3760/cma.j.issn.0254-9026.2015.04.015
- VernacularTitle:术前预防性肠外营养支持对进展期胃癌预后的影响
- Author:
Dingming ZHOU
;
Dong LUO
;
Guanhua LI
;
Tianjin CHEN
;
Can GUO
- Publication Type:Journal Article
- Keywords:
Parenteral nutrition;
Stomach neoplasms;
Prognosis
- From:
Chinese Journal of Geriatrics
2015;34(4):397-399
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the effect of preoperative prophylactic parenteral nutrition on prognosis of advanced gastric cancer.Methods A total of 159 patients with advanced gastric cancer in our hospital were collected,and randomly divided into experimental group and control group.80 cases in experimental group were treated with prophylactic parenteral nutrition,and 79 cases in control group were treated with traditional nutrition.The partial indexes of liver function,complications and mortality rate were compared between the two groups before and after surgery.Results The levels of aspartate aminotransferase (AST),alanine aminotransferase (ALT),total bilirubin (TBIL) and direct bilirubin (DBIL) were much lower in experimental group than in control group at 8 days after surgery (t=6.542,6.460,5.634,5.275,all P＜0.001).The levels of ALB and PAB were much higher in experimental group than in control group at 2 and 8 days after surgery (t=12.580,12.471,6.757,12.821,all P＜0.001).The incidence of complications and mortality rate were much lower in experimental group than in control group (x2 =23.409,4.818,P＜0.001 or 0.05).Conclusions Preoperative prophylactic parenteral nutrition can speed up the recovery of liver function and reduce the complications and mortality rate after surgery in patients with advanced gastric cancer.
