The therapeutic improvement of pediatric acute myeloid leukemia
10.3760/cma.j.issn.1673-4408.2015.02.012
- VernacularTitle:儿童急性髓系白血病的治疗进展
- Author:
Weimei SUN
- Publication Type:Journal Article
- Keywords:
Acute myeloid leukemia;
Chemotherapeutic regimen;
Targeted therapy;
Children
- From:
International Journal of Pediatrics
2015;42(2):159-162
- CountryChina
- Language:Chinese
-
Abstract:
Acute myeloid leukemia(AML) is a heterogeneous kind of disease,which is accounting for 15% ~ 20% of all tumors diagnosed in children under 15 years of age.In the past few decades,remarkable improvements have been yielded in long-term outcomes for children with AML.A better risk-group stratification of disease,which is based on clinical and biological features,a more effective use of anti-leukemia agents and enormous improvements in supportive care have increased the rate of cure by approximately 60%.This paper review the new improvements in the chemotherapeutic regimens and drugs.