The mechanisms of Toil-like receptor 4 in metabolic inflammatory response in childhood obesity
10.3760/cma.j.issn.1673-4408.2015.02.010
- VernacularTitle:Toll样受体4在儿童肥胖代谢性炎症反应中的作用机制
- Author:
Jing XIA
- Publication Type:Journal Article
- Keywords:
Childhood obesity;
Toll-like receptor 4;
Metaflammation
- From:
International Journal of Pediatrics
2015;42(2):152-155
- CountryChina
- Language:Chinese
-
Abstract:
Childhood obesity is a huge problem threatening children's health,which has reached epidemic proportions around the world and is associated with several metabolic and cardiovascular complications.Tolllike receptor 4 is a transmembrane receptor of the innate immune system.Studies have showed that metaflammation reaction mediated by inflammatory signaling pathways of Toll-like receptor 4 is closely related to childhood obesity.In this paper,studies on childhood obesity and TLR4 are reviewed.