Beta-2 adrenergic receptor agonists and acute respiratory distress syndrome
10.3760/cma.j.issn.1673-4912.2014.12.002
- VernacularTitle:β2肾上腺素受体激动剂在急性呼吸窘迫综合征中的应用
- Author:
Qi ZHANG
- Publication Type:Journal Article
- Keywords:
Beta-2 adrenergic receptor agonists;
Acute respiratory distress syndrome
- From:
Chinese Pediatric Emergency Medicine
2014;21(12):752-755
- CountryChina
- Language:Chinese
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Abstract:
Acute respiratory distress syndrome is a serious disease and has a high mortality rate.Protective ventilation strategy and conservative fluid management is the mainstay of treatment and there is no effective pharmacological treatment yet.Recent studies found that beta-2 adrenergic receptor agonists in the treatment of acute respiratory distress syndrome could inhibit the inflammatory response,protect the functions of alveolar capillary barrier,improve pulmonary edema fluid removal,promote the secretion of surfactant and enhance the impaired lung repair,and so on.This review aimed for the pathogenesis,mechanism of action and treatment mechanism of the recent studies.