The efficacy of urinary kallidinogenase plus batroxobin in the treatment of acute cerebral infarction

VernacularTitle:尤瑞克林联合巴曲酶治疗急性脑梗死的疗效观察
Author: Junning MO ; Youjia LI ; Yan HUANG
Publication Type:Journal Article
Keywords: Brain ischemia; Batroxobin; Urinary kallidinogenase
From: Chinese Journal of Primary Medicine and Pharmacy 2015;22(2):178-180
CountryChina
Language:Chinese
Abstract: Objective To observe the efficacy of urinary kallidinogenase plus batroxobin in the treatment of acute cerebral infarction.Methods 105 patients with acute cerebral infarction were selected and divided into 3 groups:urinary kallidinogenase group (35 cases),combined treatment group (39 cases),batroxobin group (31 cases).The NIHSS score,Barthel Index,MRS score were evaluated before treatment and 10 days after treatment,and the clinical efficacy was compared.Results The NIHSS score significantly decreased after treatment in the three groups (all P ＜ 0.05).The effective rate of combined treatment group was better than that of the single treatment group (urinary kallidinogenase group or batroxobin group) [79.5 ％ (31/39),71.4 ％ (25/35),35.4％ (11/31) (x2 =15.801,P =0.001)].The Barthel Index and MRS score of combined treatmentgroup were better than those of the batroxobin group (P =0.003),not better than the urinary kallidinogenase group (P =0.766).Conclusion Urinary kallidinogenase plus batroxobin is effective in the treatment of acute cerebral infarction.