Preparative separation and purification of deoxyschizandrin from Schisandrae Sphenantherae Fructus by high-speed counter-current chromatography
- Author:
Xinying LI
;
Mei YANG
;
Jieyun HUANG
;
Xiaoxue YU
;
Minqian ZHAO
;
Zhikun LIANG
;
Zhisheng XIE
;
Xinjun XU
- Publication Type:Journal Article
- Keywords:
Schisandrae Sphe-nantherae Fructus;
High-speed counter-cur-rent chromatography (HSCCC);
Deoxyschizandrin
- From:
Journal of Pharmaceutical Analysis
2013;(6):429-433
- CountryChina
- Language:Chinese
-
Abstract:
A high-speed counter-current chromatography (HSCCC) method was successfully developed for the preparative separation and purification of deoxyschizandrin from Schisandrae Sphenantherae Fructus in one step. The purity of deoxyschizandrin was 98.5%, and the structure was identified by MS, UV and NMR. This method was simple, fast, convenient and appropriate to prepare pure compound as reference substances for related research on Schisandrae Sphenantherae Fructus.
