Effectiveness and safety of live attenuated influenza vaccine in children of 2 to 17 years old
10.3760/cma.j.issn.1673-4408.2015.01.027
- VernacularTitle:减毒流感活疫苗在2～17岁儿童中的有效性和安全性
- Author:
Yilong WANG
- Publication Type:Journal Article
- Keywords:
Influenza vaccines;
Live attenuated;
Inactivated;
Efficacy;
Safety;
Children
- From:
International Journal of Pediatrics
2015;42(1):90-93
- CountryChina
- Language:Chinese
-
Abstract:
Live attenuated influenza vaccine (LAIV) is a Live attenuated influenza vaccine.LAIV has demonstrated significantly greater protection against influenza in healthy children or children with a history of respiratory diseases or with immunodeficiency diseases 2 to17 years of age as compared with TIV.LAIV can prevent influenza more efficient without increasing hospitalization and emergency department visits as compared with TIV.Except for the runny nose and nasal congestion,no excess risk of adverse events have been found among children who were vaccinated with LAIV compared with those vaccinated with TIV.LAIV has the potential in children to stimulate greater local anti-influenza immune responses and its protective effect can extend beyond the year of administration.Vaccining LAIV is convenient and noninvasive for children,it is easily accepted by children and their parents.LAIV offers a effective approach to prevent influenza.
