Application of somatostatin and its analogues in children with sepsis
10.3760/cma.j.issn.1673-4408.2015.01.016
- VernacularTitle:生长抑素及其类似物在脓毒症患儿中的应用
- Author:
Qiong WU
- Publication Type:Journal Article
- Keywords:
Somatestatin analogues;
Sepsis;
Children
- From:
International Journal of Pediatrics
2015;42(1):51-54
- CountryChina
- Language:Chinese
-
Abstract:
Somatostatin is a regulatory peptide,widely distributed in the brain,pancreas and gastrointestinal tract.Clinically,somatostatin and its analogues have been widely used in the treatment of diseases such as acute pancreatitis.Based on studies on the mechanism,such as inhibiting of inflammatory reaction,reducing endotoxin level,inhibiting oxidative damage,enhancing immune function,protecting cells and reducing ischemiareperfusion injury,it may play a certain role in sepsis,especially in the comorbidity or secondary to pancreatic and gastrointestinal damage.Somatostatin is relatively safe in clinical application.
