Traditional Chinese medicine enema and probiotics in the treatment of ulcerative colitis
10.3760/cma.j.issn.1008-6706.2015.01.032
- VernacularTitle:中药灌肠联合微生态制剂治疗溃疡性结肠炎临床研究
- Author:
Chang GE
;
Jing KUANG
- Publication Type:Journal Article
- Keywords:
Enema;
Drugs,chinese herbal;
Sulfasalazine;
Colitis,ulcerative
- From:
Chinese Journal of Primary Medicine and Pharmacy
2015;22(1):93-95
- CountryChina
- Language:Chinese
-
Abstract:
Objective To explore the clinical curative effect of traditional Chinese medicine enema,amino salicylic acid preparation and probiotics in the treatment of ulcerative colitis.Methods 168 patients were selected as the research objects which were confirmed by endoscopic examination and the diagnosis of ulcerative colitis patients,randomly divided into the control group of 84 cases and observation group of 84 cases.The control group was given with sulfasalazine(SASP) treatment,a dose of 1g,4 times/d,period of treatment was 28d.In the observation group,oral SASP treatment combined with microecological preparation often meian and traditional Chinese medicine enema,Chang An capsule,2 capsules (500mg)/time,3 times/d,postprandial oral; Herbal Enema with angelica,white lentils,flavescent sophora root,cicada,windproof suffering after filtering,every night before bed retention enema.The clinical efficacy was compared between the two groups.Results After the treatment,the Sutherland index of the observation group was (1.82 ± 1.65),which was significantly lower than (5.51 ± 1.59) of the control group (t =10.436,P < 0.05).In observation group,the clinical total effective rate,the total efficiency of endoscopic and histological total effective rate was 88.1%,81%,76.2%,the control group were 66.7%,57.1%,50%,the two groups had significant difference(x2 =4.353,4.512,5.113,P<0.05).Conclusion The traditional Chinese medicine enema,amino salicylic acid preparation and probiotics in the treatment of ulcerative colitis has good curative effect,can relieve the clinical symptoms of patients,improve the degree of intestinal diseases.