Research progress of estimating glomerular filtration rate in chronic kidney disease
10.3760/cma.j.issn.1009-9158.2014.12.007
- VernacularTitle:估算肾小球滤过率在慢性肾脏疾病诊疗中的研究现状
- Author:
Beili WANG
;
Wei GUO
;
Baishen PAN
- Publication Type:Journal Article
- Keywords:
Renal insufficiency,chronic;
Glomerular filtration rate;
Creatinine;
Cystatin C
- From:
Chinese Journal of Laboratory Medicine
2014;37(12):899-902
- CountryChina
- Language:Chinese
-
Abstract:
The mortality of chronic kidney disease (CKD) is increasing because of renal failure,cardiovascular diseases and other reasons which has been a global public health problem.Glomerular filtration rate (GFR) is the important biomarker of kidney function evaluation and early diagnosis of CKD,whose direct measurement methods cannot be widely applied in clinical laboratory.With the development of studies on estimating glomerular filtration rate (eGFR) equations,eGFR has been a biomarker of kidney function evaluation in clinical diagnosis.The current paper reviews the research progress and clinical application of different eGFR equations.