Clinical efficacy of non-steroidal anti-inflammatory drugs and α1-adrenergic antagonist on the patients with ureteral stones
10.3760/cma.j.issn.1008-6315.2014.12.016
- VernacularTitle:非甾体类抗炎药联合α1受体阻滞剂治疗输尿管结石的临床效果
- Author:
Yang QIN
;
Xianhua XU
;
Gaili LI
;
Yejin LI
;
Quanrong PAN
;
Jing XU
;
Lijuan FAN
- Publication Type:Journal Article
- Keywords:
Ureteral stones;
Non-steroidal anti-inflammatory drugs;
α1-adrenergic antagonist;
Meperidine hydrochloride
- From:
Clinical Medicine of China
2014;30(12):1284-1286
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the clinical effect of non-steroidal anti-inflammatory drugs and αl-adrenergic antagonist on treating patients with ureteral stones.Methods A total of 128 patients with ureteral colic due to ureteral stones were randomly divided into control and treatment group,and 64 cases in each group.Both two groups were treated with tamsulosin 0.4 mg oral,intravenous injection of saline 1000 mL Patients in treatment group were received intramuscular non-steroidal anti-inflammatory drugs(10 mg) and patients in control group were received pethidine hydrochloride(10 mg).Ultrasound exam were performed after 6-8 h to evaluate the stone expulsive rate.Extracorporeal shock wave lithotripsy and other treatment were underwent when the stone was still not discharge.Results The effective rate of analgesia was 96.9％ (62/64) in treatment group and 100％ (64/64) in control group(x2 =2.03,P =0.50).The stone expulsion rate in treatment group was 28.1％ (18/64),higher than that in control group(12.5％ (8/64),x2 =4.83,P =0.05).Conclusion It is effective to relive ureteral cohc with non-steroidal anti-inflammatory drugs only,and it is better than pethidine in promote stone expulsion when they both used with α1-adrenergic antagonist.
