Surgical management of pancreatic neuroendocrine neoplasms
10.3760/cma.j.issn.1673-9752.2014.10.004
- VernacularTitle:胰腺神经内分泌肿瘤的手术治疗
- Author:
Junli WU
;
Yi MIAO
- Publication Type:Journal Article
- Keywords:
Neuroendocrine neoplasms;
Pancreas;
Therapy;
Surgery
- From:
Chinese Journal of Digestive Surgery
2014;13(10):763-767
- CountryChina
- Language:Chinese
-
Abstract:
Pancreatic neuroendocrine neoplasms (pNENs) can be divided into functional and non-functional.Insulinomas,gastrinomas,glucagonomas and VIPomas are the common types of pNENs.Radical resection is the only way for curing pNENs or for a long-time survival of patients.The basic surgical procedures for pNENs are consist of local resection (tumor enucleation) or anatomical resection [pancreatoduodenectomy (standard or pylorus-preserving pancreatoduodenectomy),distal pancreatectomy (combined with splenectomy or spleen-preserving pancreatectomy) and middle segmental pancreatectomy].Liver is the most common site for metastases.Surgical resection is the method of choice for liver metastases.Radiofrequency ablation,transcatheter arterial chemoembolization and liver transplantation could be the adjunctive therapies.