Effects of Different PEEP on Abdominal Pressure and Liver in COPD Patients
10.3969/j.issn.0253-9896.2014.06.025
- VernacularTitle:不同呼气末正压对COPD患者腹腔压力及肝脏的影响
- Author:
Yating ZHANG
;
Xiaoyun ZHAO
;
Yuechuan LI
- Publication Type:Journal Article
- Keywords:
respiration,artificial;
portal vein;
liver function tests;
pulmonary disease,chronic obstructive;
PEEP;
ab-dominal pressure
- From:
Tianjin Medical Journal
2014;(6):599-601
- CountryChina
- Language:Chinese
-
Abstract:
Objective To research the impact of various PEEP parameters of mechanical ventilation on liver mor-phology and function and on hemodynamics. Methods Fifty patients of respiratory failure due to COPD using mechanical ventilation was observed by prospective, exoterical and self-control methods after their condition were stabilized. The varia-tion of abdominal pressure was measured with different PEEP of 0 cmH2O, 5 cmH2O and 10 cmH2O with mechanical ventila-tion, and measured when patients breathe autonomously with tracheostomy tube. The changes of liver morphology, hepatic por-tal vein diameter, hemodynamics and liver function were also measured on above circumstances. Results With PEEP value increases:the abdominal pressure (IAP) rise (P＜0.01) while liver morphology, function and hepatic portal did not change markedly evidently (P>0.05). By contrast, blood flow of hepatic portal vein reduced with PEEP increase (P＜0.05). Conclu-sion Higher PEEP values on mechanical ventilation will causes abdominal pressure increases and low blood flow of hepatic portal , but not obvious impact on portal vein diameter and liver function.
