Research progress of assessment of minimal residual disease in acute myeloid leukemia
10.3760/cma.j.issn.1009-9921.2013.05.022
- VernacularTitle:急性髓系白血病患者微小残留病检测的研究进展
- Author:
Hua XUE
- Publication Type:Journal Article
- Keywords:
Leukemia,myloid,acute;
Minimal residual disease
- From:
Journal of Leukemia & Lymphoma
2013;22(5):318-320
- CountryChina
- Language:Chinese
-
Abstract:
Assessment of minimal residual disease (MRD) in acute myeloid leukemia (AML) patients is now possible by using updated methods including real-time quantitative PCR (RQ-PCR) for abnormal fusion transcripts and multiparameter flow cytometry (MFC) for detecting leukemia-associated phenotypes.Using these techniques,MRD analysis has shown value in terms of risk assessment,continued patient monitoring,and therapeutic decision-making.
