Role of NADPH oxidases in oxidative stress after ischemic stroke
10.3760/cma.j.issn.1673-4165.2014.10.011
- VernacularTitle:NADPH氧化酶在缺血性卒中后氧化应激中的作用
- Author:
Wenjie YANG
;
Yun XU
- Publication Type:Journal Article
- Keywords:
Stroke;
Brain Ischemia;
NADPH Oxidase;
Oxidative Stress;
Reactive Oxygen Species
- From:
International Journal of Cerebrovascular Diseases
2014;22(10):787-792
- CountryChina
- Language:Chinese
-
Abstract:
Oxidative stress phys a very important role in the cerebral ischemia-reperfusion injury.The role of NADPH oxidases (NOX) in oxidative stress after ischemic stroke has been paid more attention and may become a new therapeutic target.This article sums up the major research progress between NOX and cerebral ischemia-reperfusion injury,discusses the characteristics of various isozymes and their relationship with stroke,further investigates the pathogenesis of stroke from the perspective of NOX,and provides a new idea for the prevention and treatment of ischemic stroke.
