Roles of microRNA miR-124 in cerebral ischemia
10.3760/cma.j.issn.1673-4165.2014.09.016
- VernacularTitle:微小RNA miR-124在脑缺血中的作用
- Author:
Changfeng FAN
;
Di YU
;
Xuming MO
- Publication Type:Journal Article
- Keywords:
Brain Ischemia;
MicroRNAS;
Apoptosis;
Neuroprotective Agents
- From:
International Journal of Cerebrovascular Diseases
2014;22(9):712-715
- CountryChina
- Language:Chinese
-
Abstract:
MicroRNAs (miRNAs) are a class of highly conserved small noncoding single stranded RNAs.They participate in the regulation of target genes through the degradation of mRNA and/or inhibition of translation.As the most abundant miRNAs in the central nervous system,miRNA-124 (miR-124) has been widely given attention in recent years.The recent research suggests that miR-124 is closely associated with ischemic cerebral injury,but its specific regulation mechanism remains unclear.This article reviews the roles of miR-124 in ischemic cerebral injury.
