Observation on the curative effect of recombinant bovine basic fibroblast growth factor gel combined with esberitox for recurrent oral ulcer
10.3760/cma.j.issn.1673-4904.2014.36.003
- VernacularTitle:重组牛碱性成纤维细胞生长因子外用凝胶联合施保利通治疗复发性口腔溃疡疗效观察
- Author:
Dali QU
;
Qun JIANG
;
Yunyun SUN
- Publication Type:Journal Article
- Keywords:
Fibroblast growth factors;
Oral ulcer;
Gels;
Esberitox
- From:
Chinese Journal of Postgraduates of Medicine
2014;37(36):6-7
- CountryChina
- Language:Chinese
-
Abstract:
Objective To observe the clinical effect of recombinant bovine basic fibroblast growth factor gel combined with esberitox for recurrent oral ulcer.Methods Forty-six patients with recurrent oral ulcer were divided into treatment group of 22 patients and control group of 24 patients by random digits table method.The patients in treatment group were given recombinant bovine basic fibroblast growth factor gel and esberitox.The patients in control group were given the watermelon frost spray only.After treatment for 1 week,the curative effect was compared.Results The cure rate in treatment group was 90.9％ (20/22),which was significantly higher than that in control group (66.7％,16/24),and there was significant difference (P ＜0.05).The time of pain vanish,oral ulcer decrease,oral ulcer healing in treatment group were significantly shorter than those in control group,and there were significant differences (P ＜0.05).Conclusions Recombinant bovine basic fibroblast growth factor gel combined with esberitox for recurrent oral ulcer can promote ulcer healing,shorten the course of disease,and has no adverse reaction.It is worthy of applying in clinic.
