New oral anticoagulants for preventing ischemic stroke in patients with atrial fibrillation
10.3760/cma.j.issn.1673-4165.2014.08.006
- VernacularTitle:新型口服抗凝药预防心房颤动患者的缺血性卒中
- Author:
Shuying CHEN
;
Ying PENG
- Publication Type:Journal Article
- Keywords:
Stroke;
Brain Ischemia;
Atrial Fibrillation;
Anticoagulants;
Administration,Oral;
Thrombin;
Factor Xa
- From:
International Journal of Cerebrovascular Diseases
2014;22(8):606-613
- CountryChina
- Language:Chinese
-
Abstract:
New oral anticoagulants,including direct thrombin inhibitors and factor Xa inhibitors.They have overcome several shortcomings of warfarin.The efficacy of preventing stroke and systemic embolism is superior to or not inferior to warfarin in patients with non-valvular atrial fibrilhtion,and they can decrease the risk of bleeding (especially intracranial hemorrhage).However,no agent can efficiently reverse its anticoagulant effect now.This article reviews the pharmacological characteristics,clinical efficacy,complications,and its management of the commonly used new oral anticoagulants at present.
