Association between subclinical hypothyroidism and albuminuria in type 2 diabetes mellitus patients

VernacularTitle:2型糖尿病患者亚临床甲状腺功能减退症与微量白蛋白尿的关系研究
Author: Hengchi YU ; Xu HONG ; Jie YIN ; Yabin HAO ; Qi DUAN ; Bing LIU
Publication Type:Journal Article
Keywords: Hypothyroidism; Diabetes mellitus,type 2; Albuminuria
From: Chinese Journal of Postgraduates of Medicine 2014;37(34):36-38
CountryChina
Language:Chinese
Abstract: Objective To determine the relationship between subclinical hypothyroidism (SCH) and the prevalence of albuminuria in type 2 diabetes mellitus.Methods A total of 826 type 2 diabetes mellitus patients without thyroid disease were enrolled.Participants were evaluated for glycemic control,thyroid function,and albuminuria in a cross-sectional analysis.Results Of 826 type 2 diabetes mellitus,780 subjects were euthyroid(94.44％,780/826) and 46 had SCH (5.56％,46/826).The patients with SCH had a higher proportion in women and higher body mass index compared with the patients with euthyroid [69.6％(32/46) vs.49.7％(388/780),(26.7 ± 4.0) kg/m2 vs.(25.1 ± 3.8) kg/m2],and there was significant difference(P ＜ 0.01).No significant difference in glycated hemoglobin and the prevalence of albuminuria was found between the patients with SCH and the patients with euthyroid (P ＞ 0.05).Conclusion SCH is not a risk factor for albuminuria in type 2 diabetes mellitus.