A Review of Cardiac Myxoma: 33-year Experience in a Single Institution.
10.4070/kcj.1998.28.7.1131
- Author:
Woong Chol KANG
1
;
Jong Won HA
;
Byung Chul CHANG
;
Jin Wuk KWON
;
Se Joong RIM
;
Namsik CHUNG
;
Seung Yun CHO
;
Sung Soon KIM
;
Meyun Shick KANG
;
Sang Ho CHO
;
Bum Koo CHO
Author Information
1. Cardiology Division, Yonsei University, College of Medicine, Seoul, Korea.
- Publication Type:Original Article
- Keywords:
Cardiac myxoma;
Systemic embolism;
Echocardiography;
Surgical excision
- MeSH:
Diagnosis;
Early Diagnosis;
Echocardiography;
Embolism;
Female;
Follow-Up Studies;
Heart Atria;
Humans;
Incidence;
Male;
Medical Records;
Mortality;
Myxoma*;
Recurrence;
Reoperation
- From:Korean Circulation Journal
1998;28(7):1131-1140
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
BACKGROUND AND OBJECTIVES: Cardiac myxomas are uncommon. Early diagnosis and treatment are essential to reduce morbidity or mortality. Before 1970, preoperative diagnosis was difficult. With the development of echocardiography, a correct diagnosis is made before operation. We reviewed our clinical experience in diagnosis and management of 52 cases of myxomas seen over a 33-year period, 1966 to 1998. PATIENTS AND METHODS: There were 20 males (38%) and 32 females (62%);age range 7 - 80. All the patient's medical records were reviewed. In twenty-five patients in whom echocardiographic features could be reviewed, clinical fetures were compared according to two distinct echocardiographic features;Round and polypoid type. RESULTS: Eighty-four percents of the presenting symptoms were cardiac origin while systemic embolism (SE) accounted for 15%. Echocardiography was used most often for diagnosis. The myxomas were located in the left atrium in 50 (96%), right atrium in 2 (4%). One patient had multiple myxoma. The incidence of SE was significantly higher in polypoid type than in round type (58% vs 0%, p<0.05). Multivariate regression analysis revealed polypoid type was the only independent predictor of SE (p=0.0029). Follow-up duration was ranged from 1 to 266 months. There was no deaths associated with myxoma. One patient presented with a recurrence 3 years after resection, and reoperation was performed uneventfully. CONCLUSION: Due to the nonspecific presentation of myxoma, a high index of suspicion is needed. Surgical excision of myxoma can be considered curative with excellent long-term result. However, because of high possible occurrence of SE, a close attention should be given to those patients who have myxoma of polypoid type.
