Diagnostic value of serum procalcitonin and C-reactive protein in patients with lower respiratory tract diseases

VernacularTitle:血清降钙素原和C反应蛋白对下呼吸道感染的诊断价值
Author: Xuefeng LI ; Houzhao WANG ; Zejin XIE ; Wei YANG
Publication Type:Journal Article
Keywords: Procalcitonin; C-reactive protein; Lower respiratory tract infection
From: Clinical Medicine of China 2014;30(10):1044-1045
CountryChina
Language:Chinese
Abstract: Objective To explore the early diagnosis value of serum procalcitonin (PCT) and Creactive protein (CRP) on lower respiratory tract diseases.Methods Two hundred patients with lower respiratory tract diseases were selected as our subjects.Serum PCT and CRP levels were measured and analyzed before and after treatment.Results Serum PCT of 90 patients with bacterium infection before and after treatment were (4.23 ± 3.48) μg/L and (1.90 ± 0.90) μg/L respectively; and serum CRP were (62.38 ± 17.13) mg/L and (9.55 ±3.52) mg/L.Serum PCT and CRP of the patients with bacterium infection after treatment were statistically different from that before treatment (t =6.149,29.96 ; P ＜ 0.01).Serum PCT and CRP of patients with bacterium infection was statistically different from those of patients with virus infection or no infection(F =41.04,12.89 ;P ＜ 0.01).Conclusion Serum PCT and C-reactive protein show significant value in early diagnosis in lower respiratory tract infection.Dynamically testing them will help to assessment of curative efficacy.