Curative effect of Aidi injection solution combined with carboplatin on controlling malignant pleural effusion
10.3760/cma.j.issn.1008-6315.2014.10.010
- VernacularTitle:艾迪注射液联合卡铂控制恶性胸腔积液的效果观察
- Author:
Yanhong LIU
;
Yanyan ZHAO
- Publication Type:Journal Article
- Keywords:
Malignancy;
Aidi injection solution;
Carboplatin;
Pleural effusion
- From:
Clinical Medicine of China
2014;30(10):1035-1037
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the curative effect of Aidi injection solution combined withcarboplatin on controlling malignant pleural effusion(MPE).Method A total of 86 cancer patients with appearedPME were selected as our subjected who hospitalized in the First People's Hospital of Shangqiu from Feb.2012to Mar.2013.They were randomly divided into the observation group(43 cases) and the control group(43cases).Patients in the oontrol group were treated with carboplatin at dose of 100 mg/per times which was putinto the thoracic cavity,and patients in the observation group was treated with Aidi injection solution at dose of100 mg/per times beside carbeplatin.The treatment period was 4 weeks.The effect information,quality of lifeand adverse reactions were recorded.Results The total effective rate and survival quality improvement rate inobservation group were 86.05％ (37/43) and 51.16％ (22/43),higher than those in control group (67.44％(19/43),30.23％ (13/43)),and the differences were significant(x2 =4.170,3.903 ; P ＜ 0.05).There wasno significant difference in terms of the related adverse reactions between two groups(P ＞0.05).ConclusionThe therapy of Aidi injection solution plus carboplatin on controlling MPE is proved to be effective and it canimprove patients' quality of life with better safety.Therefore it is worthy of recommendation.
