Gallbladder sarcomatoid carcinoma:six cases and literature review
10.3969/j.issn.1000-8179.20142106
- VernacularTitle:胆囊肉瘤样癌6例及文献复习
- Author:
Yanzi QIN
;
Yurong OU
;
Li MA
;
Qiong ZHANG
;
Shiwu WU
;
Ligao WU
;
Yisheng TAO
- Publication Type:Journal Article
- Keywords:
sarcomatoid carcinoma;
cytokeratin;
vimentin;
immunohistochemistry
- From:
Chinese Journal of Clinical Oncology
2015;46(4):247-250
- CountryChina
- Language:Chinese
-
Abstract:
Objective: To investigate the clinicopathological features, diagnosis, and differential diagnosis of gallbladder sarcomatoid carcinoma. Methods: The clinical manifestations and the microscopic and immunohistochemical characteristics of six patients with gallbladder sarcomatoid carcinoma were analyzed with a follow-up period. Related literature was reviewed. Results:Immunohistochemical markers of gallbladder sarcomatoid carcinoma with spindle cell morphology were epithelial and mesenchymal positivity. Conclusion: Gallbladder sarcomatoid carcinoma could be firmly diagnosed by microscopic morphology and immunohistochemistry. Radical resection is currently used to treat such patients. However, more cases with longer follow-up period are needed to discover better treatments and improve the survival of these patients.
