Antibiotic resistance patterns of uropathogens in 141 children hospitalized with complicated urinary tract infection
10.3760/cma.j.issn.1673-4904.2014.33.011
- VernacularTitle:141例住院儿童复杂性尿路感染致病菌及耐药分析
- Author:
Xiaoyan PAN
;
Wenqiang CHEN
;
Yan YUAN
- Publication Type:Journal Article
- Keywords:
Children;
Complicated urinary tract infection;
Antibiotic resistance;
Uropathogen;
Empirical treatment
- From:
Chinese Journal of Postgraduates of Medicine
2014;37(33):30-33
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the distribution and antibiotic resistance patterns of uropathogens in children with complicated urinary tract infection to guide the empirical antimicrobial treatment.Methods Retrospective analysis of isolated bacteria from 141 children hospitalized with complicated urinary tract infection was performed from January 2011 to January 2013.Results Gram-negative bacillus were the main pathogens [56.6％(81/143)],and Escherichia coli was the leading cause (41.3％,59/143).Gram-positive bacillus accounted for 38.5％ (55/143),including Enterococcus faecium (17.5％,25/143) and Enterococcus faecalis (14.7％,21/143).Fungi caused 4.9％ (7/143) of the infections.The resistance of Escherichia coli to amoxicillin was the highest [92.0％ (23/25)] and resistance to imipenem (4.3％,2/47),amikacin (6.8％,4/59) and nitrofurantoin (6.8％,4/59) was lower.It was observed resistance of Enterococcus faecium to linezolid,quinupristin,vancomycin and nitrofurantoin was significantly lower than other common antibiotics.The resistance of Enterococcus faecalis to quinupristin,tetracycline,erythromycin,rifampicin was significantly higher than other common antibiotics.Concluusions Escherichia coli,Enterococcus faecium and Enterococcus faecalis are the common uropathogens.These pathogens have a high antibiotic resistance to many common antibiotics.The selection of empirical treatment of children with complicated urinary tract infection should be adjusted by antimicrobial susceptibility test.
