Acellular dermis combined with sodium hyaluronate in the reconstruction of tendon sheath
10.3969/j.issn.2095-4344.2014.43.009
- VernacularTitle:脱细胞异体真皮结合玻璃酸钠在腱鞘重建中的应用
- Author:
Zelong CUI
- Publication Type:Journal Article
- From:
Chinese Journal of Tissue Engineering Research
2014;(43):6940-6944
- CountryChina
- Language:Chinese
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Abstract:
BACKGROUND:Acellular al ogeneic dermis that is replaced by autologous tissue is not considered as foreign body, and can reduce local inflammation and cellinfiltration, to achieve the possibility of permanent retention in the body after reconstruction of the tendon sheath. ＜br> OBJECTIVE:To evaluate the efficacy of acellular dermal matrix combined with sodium hyaluronate to prevent adhesiolysis after adhesions of tendon during the procedure of tendon sheath reconstruction. ＜br> METHODS:A total of 56 patients who required secondary adhesiolysis to repair tendon adhesions after repair of wrist tendon injury were randomly separated into experimental group (26 cases) and control group (30 cases). Experimental group:after tendon release, the sleeve-shaped acellular dermal matrix with a large diameter than the tendon was sewn into the site of tendon adhesions, 1 cm distant to the distal and proximal ends of non-adhesion tendon, to reconstruct the tendon sheath that was fixed at the both ends of surrounding tissue. Then, the incision was sutured after injection of sodium hyaluronate via the sleeve. Control group:after tendon release, the wound was sutured directly. Al of the patients were fol owed-up for 6 months, to compare the efficacy of tendon release and reoccurrence of adhesions. ＜br> RESULTS AND CONCLUSION:For 51 tendons from 26 patients in the experimental group, valid treatment was in 49 tendons and invalid in 2 tendons, with the effective rate of 96%;for 58 tendons from 30 patients in the control group, effective treatment was in 46 tendons, and invalid in 12 tendons, with the effective rate of 79%. There was a significant difference in the effective rate between the two groups (P＜0.05). The reconstruction of tendon sheath using acellular dermal matrix combined with sodium hyaluronate can effectively improve adhesions after adhesiolysis.
