Application of nanobodies in molecular imaging
10.3760/cma.j.issn.2095-2848.2014.06.027
- VernacularTitle:纳米抗体在肿瘤分子显像中的应用
- Author:
Xiaoliang ZHOU
;
Hao WANG
;
Jianfeng LIU
;
Aimin MENG
- Publication Type:Journal Article
- Keywords:
Single-domain antibodies;
Molecular imaging;
Neoplasms;
Trends
- From:
Chinese Journal of Nuclear Medicine and Molecular Imaging
2014;34(6):521-522
- CountryChina
- Language:Chinese
-
Abstract:
Nanobodies,which occur naturally in Camelidae animals,are the functional heavy chain antibodies without light chains.Having the relative properties of small size,high stability,good solubility and targeting effect,nanobodies have a great potential in PET and SPECT imaging for the diagnosis and treatment of diseases,such as tumor and infectious disease.Radio-labeled nanobodies might have potential to become the molecular imaging probes of the next generation.
