Surgical treatment of Marfan syndrome of pregnancy complicated with acute type A aortic dissection

VernacularTitle:马凡综合征妊娠合并主动脉A型夹层的外科治疗
Author: Hui WANG ; Yong ZHANG ; Jiali LIANG ; Ming CHEN
Publication Type:Journal Article
Keywords: Pregnancy; Marfan syndrome; Type A aortic dissection
From: Chinese Journal of Postgraduates of Medicine 2014;37(32):33-35
CountryChina
Language:Chinese
Abstract: Objective To summarize the experience in the treatment of Marfan syndrome of pregnancy complicated with acute type A aortic dissection.Methods Three women with Marfan syndrome of pregnancy complicated with acute type A aortic dissection were treated.The average age was 28.6 (25-31) years,and the average gestational age was 36.5 (32-38) weeks.At first caesarean operation were performed under general anesthesia.Bentall + Sun' s operation was performed under deep hypothermic circulatory.After operation,the mother and fetus were followed up.Results Three women and their fetus were safe.The average extracorporeal circulation time,aorta clamp time and circulatory arrest time were 265 (210-280) min,135 (120-160) min and 26.5 (20-29) min,respectively.After a mean follow-up of 2.0 (1.0-2.5) years,3 patients were living well.CT angiogram detected normal aortic,with no signs of distal dilation.Three fetus were normal in development and neurocognitive function.Conclusion Methods of surgical repair and fetal delivery should be chosen based on aortic pathological changes and gestational age to maximize the safety of the mother and fetus.