Recent advances in kupffer cells
10.3760/cma.j.issn.1007-8118.2015.05.021
- VernacularTitle:肝脏枯否细胞研究进展
- Author:
Hongwei SUN
;
Chenglin LI
;
Ping WANG
;
Yan CUI
- Publication Type:Journal Article
- Keywords:
Liver;
Kupffer cells;
Advances
- From:
Chinese Journal of Hepatobiliary Surgery
2015;21(5):351-353
- CountryChina
- Language:Chinese
-
Abstract:
In recent years,exciting research progress has been made on hepatic Kupffer cells.For inflammation,the study of Kupffer cells focused on its mechanism of whether and how Kupffer cells play a role in regulating inflammatory reaction,especially molecular mechanisms.For fatty liver,researchers are exploring the role of Kupffer cells in the development of fatty liver,as well as potential treatments.For the treatment of ischemia-reperfusion injury,latest protocols were based on Kupffer cells.In the area of liver transplantation,the study of Kupffer cells centered on immune tolerance and graft versus host disease (GVHD).As for tumor,current studies focused on regulatory mechanism of Kupffer cells on growth and metastasis of tumor.This article will present a review on the latest progress.
