Clinical efficacy of Deanxit in non-erosive gastroesophageal reflux disease with anxiety and depres-sion

VernacularTitle:黛力新治疗伴焦虑抑郁情绪的非糜烂性胃食管反流病的临床观察
Author: Bai LI ; Fuwen ZHANG ; Shu LI ; Fenglei WANG ; Yongqiang HE ; Jing YANG ; Xinli YANG ; Aicheng WANG
Publication Type:Journal Article
Keywords: Flupenthixol/TU; Gastroesophageal reflux/CO/DT; Anxiety; Depression
From: Journal of Chinese Physician 2015;(3):369-371
CountryChina
Language:Chinese
Abstract: Objective To investigate clinical effects of Deanxit in non-erosive gastroesophageal re-flux disease ( NERD) with anxiety and depression.Methods A total of 76 patients diagnosed NERD with anxiety and depression by endoscopy and hospital anxiety and depression scale ( HAD) were randomly divid-ed into regular treatment group and Deanxit treatment group.Clinical efficacy, symptom score, and anxiety and depression score were observed after one week, four weeks, and eight weeks.Results Deanxit signifi-cantly increased the clinical efficacy after one week ( P <0.01) and remission rate after one week ( P <0.05), four and eight weeks ( P <0.01).It improved symptoms, depression, and anxiety, which showed significant differences ( P <0.01) compared to control group after one week, four and eight weeks adminis-tration.Conclusions Deanxit can be applied in NERD with anxiety and depression treatment, which has quick effect and high remission rate, and improve patient's reflux symptoms and anxiety depression.