Correlation Analysis of Serum Omentin-1 and Serum High Sensitive C-reactive Protein in Coronary Heart Disease
10.3969/j.issn.0253-9896.2014.02.011
- VernacularTitle:冠心病患者网膜素-1与高敏C反应蛋白的相关性分析
- Author:
Hailiang LIU
;
Huixia ZHANG
;
Hao ZHANG
;
Ruibo ZHANG
;
Lijuan YANG
;
Shujing LIU
- Publication Type:Journal Article
- Keywords:
coronary heart disease;
angina pectoris;
C-reactive protein;
Omentin-1
- From:
Tianjin Medical Journal
2014;(2):135-137
- CountryChina
- Language:Chinese
-
Abstract:
Objective To evaluate the correlation of Omentin-1, the high sensitivity C-reactive protein (hsCRP) and coronary heart disease (CHD). Methods Sixty-eight patients with CHD were divided into the unstable angina pectoris (UAP) group (n=36), stable angina pectoris (SAP) group (n=32). And 30 normal subjects without CHD diagnosed by coronary arteriography (CAG) were served as the control group. The serum level of Omentin-1 was measured by enzyme linked immu-nosorbent assay (ELISA) and the serum level of hsCRP was measured by turbidmetric immunoassay. Results The serum level of Omentin-1 was significantly lower, but the serum level of hsCRP was significantly higher in CHD group than that of control group (P<0.05). The serum level of hsCRP was significantly lower in SAP group than that of UAP group (P<0.05). There was no significant difference in serum level of Omentin-1 between groups (P>0.05). The serum level of Omentin-1 was significantly lower in patients with single, double and three-vessel lesion group than that of control group, but the serum level of hsCRP was significantly higher in CHD group than that of control group (P<0.05). There were no significant differ-ence in serum levels of Omentin-1 and hs-CRP between single, double and three-vessel lesion groups (P>0.05). The se-rum level of Omentin-1 was negatively correlated with serum level of hsCRP (P<0.01). Conclusion The serum level of Omentin-1 and hsCRP may correlate with CHD, but which may not reflect the severity of artery stenosis.
