Progress in molecular diagnostic techniques for leukemia
10.3760/cma.j.issn.1009-9158.2015.03.016
- VernacularTitle:白血病分子诊断技术的研究进展
- Author:
Zhanguo CHEN
;
Yan LI
;
Yongqing TONG
- Publication Type:Journal Article
- Keywords:
Leukemia;
Molecular diagnostic techniques
- From:
Chinese Journal of Laboratory Medicine
2015;(3):206-210
- CountryChina
- Language:Chinese
-
Abstract:
With the development of molecular diagnostic techniques, the study for the etiology of leukemia has been entering the era of the molecular biology.Molecular techniques for leukemia diagnosis, prognosis and individualized therapy are used widely, becoming one of the necessary routine tests for patients with leukemia. So far, molecular techniques for leukemiaincluding cytogenetic diagnosis, molecular genetics, molecular diagnostics based on PCR, mutation detection, as well as a variety of next-generation sequencing, have played an important role in the diagnosis of leukemia, minimal residual disease monitoring, prognosis and targeted therapy.