Research progress of CD4+ CD25+ regulatory T cells in blood diseases
10.3760/cma.j.issn.1009-9921.2014.04.018
- VernacularTitle:CD4+CD25+调节性T细胞在血液病中的研究进展
- Author:
Xiaohua WANG
;
Wei SUN
- Publication Type:Journal Article
- Keywords:
CD4+ CD25+ regulatory T cells;
Blood diseases;
Immunomodulatory
- From:
Journal of Leukemia & Lymphoma
2014;23(4):250-252
- CountryChina
- Language:Chinese
-
Abstract:
CD4 + CD25 + regulatory T cells are produced in the thymus and have anergic and immunosuppressive properties.Researchers measured the antibody level related with CD4+ CD25+ T cells,CD4+ CD25hi T cells,CD4+ CD25+ Foxp3 and CD4+ CD127 in regenerative anemia,leukemia,ITP,NHL,MDS.Then they got the conclusions that regulatory T cells decreased in the autoimmune blood diseases and increased in the neoplastic diseases.The regulatory T cells have great prospect in the treatment of autoimmune diseases,allergic diseases,transplant rejection,tumors and specific vaccination.
