Clinical and laboratory features of Uyghur patients with chronic lymphocytic leukemia in Xinjiang Uyghur Autonomous Region
10.3760/cma.j.issn.1009-9921.2013.09.014
- VernacularTitle:新疆维吾尔自治区维吾尔族慢性淋巴细胞白血病患者临床与实验室检查特点分析
- Author:
Yimamu MAIMAITILI
;
Abuduer MUHEBAIER
;
Xiaomin WANG
;
Yan LI
- Publication Type:Journal Article
- Keywords:
Leukemia,lymphocytic,chronic;
Uyghur;
Clinical features;
Laboratory tests;
Therapy
- From:
Journal of Leukemia & Lymphoma
2013;22(9):555-557
- CountryChina
- Language:Chinese
-
Abstract:
Objective To analyze the clinical and laboratory features of Uyghur patients with chronic lymphocytic leukemia(CLL) in Xinjiang Uyghur Autonomous Region.Methods Retrospective investigation of 39 Uyghur patients with CLL in the People' s Hospital of Xinjiang Uyghur Autonomous Region,and analyzed 30 cases of Han nationality patients with CLL choose over the same period as the contrul group.Results The average age of Uyghur and Han nationality CLL patients were (65.6±10.4) years old and (63.9±7.9) years old while the average age was (64.7±9.0) years old of all cases,and there was no statistical significance (P =0.448).By CLL Rai staging,patients in low-risk (phase 0),medium-risk (phase Ⅰ and Ⅱ) and high-risk (phase Ⅲ and Ⅳ) were 6,24 and 39 cases respectively.Among them,Uyghur patients with advanced stage was more than Han nationality patients (P =0.039).The WBC counts in the initial diagnosis and the number of lymph node regions involved ≥3 were statistically significant (t =2.488,P =0.015,x2 =4.194,P =0.041).With a median follow-up time of 38.0 months (8.0-124.0 months),in which 10 cases died,5 cases was Uyghur and 5 cases was Han nationality,and all of them were the high-risk group of CLL patients.The expected 5-year survival rate and the median survival time were (88.0±2.7) ％ and 100.7 months,respectively and both of them shorter than Han nationality patients with CLL [(94.0±3.0) ％ and 151.1 months],but no statistically significant (x2 =2.198,P =0.138,x2 =0.583,P =0.445).Conclusion There are some differences in two nations in the case of characteristics of clinical laboratory examinations and survivals.
