Anticoagulation therapy of vascular thrombotic diseases and new progress of Rivaroxaban application
10.11958/j.issn.0253-9896.2015.04.031
- VernacularTitle:血管血栓性疾病的抗凝治疗及利伐沙班应用新进展
- Author:
Ziyuan ZHAO
;
Xiujun ZHANG
- Publication Type:Journal Article
- Keywords:
anticoagulants;
factorⅩa;
thrombosis;
review;
Rivaroxaban
- From:
Tianjin Medical Journal
2015;(4):446-448
- CountryChina
- Language:Chinese
-
Abstract:
Incidence of thrombotic disease is very high, and this disease can result in high mortality and high disability rate. Prevention and treatment of the disease mainly include:antiplatelet, anticoagulation and thrombolysis. Choice of anti?thrombotic treatment based emphasizes on individuation. As a direct inhibitor of factor Xa, Rivaroxaban exert its anticoagu?lant activity without antithrombinⅢbut is ineffective to theⅩa in prothrombin complex, which can be used as a substitute of traditional anticoagulant. In this paper, applications of Rivaroxaban on treating symptomatic venous thromboembolic dis?ease, postoperative venous thrombosis and cardiovascular thrombosis are reviewed.
