The Usefulness and Safety of Natural Stent in a Canine Model of Tracheal Stenosis.
10.4046/trd.2002.53.4.431
- Author:
Ho Joong KIM
1
;
Won Jung KOH
;
Gee Young SUH
;
Man Pyo CHUNG
;
Jhin Gook KIM
;
Soo Won SUH
;
O Jung KWON
Author Information
1. Division of Pulmonary and Critical Care Medicine, Department of Medicine, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea. ojkwon@smc.samsung.co.kr
- Publication Type:Clinical Trial ; Original Article
- Keywords:
Animal;
Airway;
Bronchoscopy
- MeSH:
Animals;
Bronchoscopy;
Dogs;
Humans;
Lasers, Solid-State;
Stents*;
Trachea;
Tracheal Stenosis*
- From:Tuberculosis and Respiratory Diseases
2002;53(4):431-438
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
BACKGROUND: In order to investigate the usefulness and safety of Natural Stent, we performed this study in a canine model of tracheal stenosis induced using Nd-YAG laser. METHODS: After tracheal stenosis was induced in 12 Mongrel dogs using Nd-YAG laser, either Dumon (n=6) or Natural (n=6) stent was inserted into the trachea. To assess the degree of stent migration and mucostasis, bronchoscopy was performed every week for 4 weeks, after which all stents were removed. One week after stent removal, tracheal stenosis was evaluated by bronchoscopy. RESULTS: The degree of stent migration was not different between the dogs with Dumon stent (3.0+/-0.8) and those with Natural (2.0+/-1.0), nor was the degree of mucostasis, at Dumon (1.7+/-0.5) and Natural Stent (1.5+/-0.6), respectively. One week after stent removal, the degree of tracheal stenosis was not different between the Dumon (1.5+/-0.5) and the Natural group (1.0+/-0.4). In addition, there was no death and the degree of tracheal stenosis remained always within the safe limit (less than 2.0) in all animals. CONCLUSION: In a canine model of tracheal stenosis induced using Nd-YAG laser, the usefulness and safety of Natural Stent were similar to those of Dumon Stent. A clinical trial is necessary to document the usefulness and safety of Natural Stent in patients with tracheal stenosis.
