A Case of Kartagener's Syndrome with Various Ultrastructural Defects.
10.4046/trd.2002.53.4.457
- Author:
Sung Ho LEE
1
;
Jung Ho PARK
;
Ho Sik JANG
;
Hyun Su KIM
;
Kyeong Woo KANG
;
Ho Chul KIM
;
Kun Young KWON
Author Information
1. Division of pulmonology, Department of Medicine, Sungkyunkwan University School of Medicine, Masan Samsung Medical Center, Masan, Korea. kangkw@samsung.co.kr
- Publication Type:Case Report
- Keywords:
Kartagener's syndrome;
Immotile cilia;
Dyskinetic cilia
- MeSH:
Arm;
Bronchiectasis;
Cilia;
Ciliary Motility Disorders;
Dyneins;
Female;
Humans;
Kartagener Syndrome*;
Microscopy, Electron;
Sinusitis;
Situs Inversus;
Spermatozoa
- From:Tuberculosis and Respiratory Diseases
2002;53(4):457-462
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
Kartagener's syndrome is an inherited condition characterized by triad of chronic paranasal sinusitis, situs inversus, and bronchiectasis. Since 1976, Afzelius found a lack of dynein arm in immotile spermatozoa by electron microscopy, numerous recent studies have focused on the ultrastructural defect in the cilia and reported that the variety type of ultrastructural defect in immotile cilia syndrome. We report a female patient who had the Kartagener's triad with rare multiple ultrastructural defect of cilia in one patient. The electron microscopic examination showed partial dynein arm defect, loss of radial spoke, microtubular transposition, and giant cilia.
